ABSTRACT
The study aimed at identifying the social, economic, health, and psychological consequences of Corona pandemic in Jordanian society, and identifying the predictive value of demographic, social, and economic variables in explaining the different repercussions of Corona pandemic on the members of Jordanian society. In order to achieve the objectives of the study, a data collection scale was designed. The sample consisted of 2570 respondents chosen randomly. The study was based on the social survey methodology. The study revealed the depth of consequences left by the pandemic on Jordanian society. They all have high averages and they are arranged in a row from the highest: Economic followed by psychological, health, and social. The study also revealed that there is a statistical effect of demographic variables on all aspects of life. This indicates the obvious impact of the independent variables included in the (regression equation) on all aspects of life: social, economic, health, and psychological life during the Corona pandemic. © 2023 DSR Publishers/ The University of Jordan.
ABSTRACT
Health care providers (HCPs) worldwide have been a common target for stigmatization during widespread infections, such as COVID-19. The purpose of this study is to highlight the prevalence of stigmatization during the COVID-19 pandemic among HCPs in Turkey using the Stigma COVID-19 HCPs instrument (S19-HCPs). Descriptive design. The S19-HCPs is a self-administered, web-based survey (24 items) developed previously. The internal consistency of the S19-HCPs' Turkish version was satisfactory (alpha = 0.79). Test-retest correlations were all statistically significant for the Turkish version of the instrument (ICC = 0.90, p0.01). Most study participants were 20-30 years old (77%);among the respondents, 66% had worked in a COVID-19-designated facility. Stigma against HCPs is highly prevalent in Turkey. The outcomes of this study revealed substantial levels of HCP stigmatization in Turkey irrespective of their motivation to work with COVID-19 patients. Education, media, and awareness campaigns might play a critical role in addressing global stigmatization issues.Copyright © 2022 The Author(s). This open access article is distributed under a Creative Commons Attribution (CC-BY) 4.0 license.
ABSTRACT
This study aims at identifying the level of psychological and social symptoms resulting from the quarantine due to the COVID-19 crisis. The sample consists of the heads of families in Jordan according to the following variables: Sex, age, and nationality. The sample number of the study is (524) respondents from both Sexes, divided into 301 females (57.4%) and 223 males (42.6). The psychological and social symptoms measures were used. The results indicated that the effect of quarantine during the COVID-19 crisis on some psychological and social aspects was moderate, there were no statistically significant differences due to the sex variable, the male interest in the physical dimension, and there were no statistically significant differences due to the age variable. In addition, there are statistically significant differences in the effect of domestic quarantine on the psychological aspects, which are attributed to the nationality variable, specifically the Jordanian class, and there are differences in the nationality variable in the social dimension for the favor of the non-Jordanian group. © 2022 DSR Publishers/The University of Jordan.
ABSTRACT
Introduction: Intravenous immunoglobulin (IVIG) has been used as an immunomodulatory therapy to counteract severe systemic inflammation in coronavirus disease 2019 (COVID19) but its use in COVID19-related acute respiratory distress syndrome (ARDS) is not well-established. Research Question or Hypothesis: Is IVIG therapy associated with lower mortality in COVID19-related ARDS? Study Design: Retrospective cohort Methods: We included adult COVID19 patients admitted to intensive care units (ICUs) at Hazm Mebaireek General Hospital, Qatar between March 7, 2020 and September 9, 2020. Patients receiving invasive mechanical ventilation for moderate-severe ARDS were divided into two groups based on whether they received IVIG therapy. Primary outcome was all-cause ICU mortality. Secondary outcomes were ventilator-free days and ICU-free days at day-28, and incidence of acute kidney injury (AKI). Propensity score matching was used to adjust for confounders. The primary outcome was compared using competing-risks survival analysis. Statistical analysis was conducted using Stata MP 16.0. P values of less than 0.05 was considered significant. Results: Among 590 patients included in the study, 400 received routine care and 190 received IVIG therapy in addition to routine care. One-hundred eighteen pairs were created after propensity score matching with no differences between the groups. The median time from ICU admission to initiation of IVIG therapy was 6.3 days (interquartile range [IQR] 2.1-11.9 days) and the median cumulative dose of IVIG received was 150 grams (IQR 105-235 grams). ICU mortality was 27.1% overall and 25.8% in the matched cohort. Mortality was higher among IVIG-treated patients (36.4% vs. 15.3%;sub-distribution hazard ratio[sHR] 3.5;95% CI 1.98-6.19;P<0.001). Ventilator-free days and ICU-free days at day-28 were lower (P<0.001 for both), and incidence of acute kidney injury was higher in the IVIG group (85.6% vs. 67.8%;P=0.001). Conclusion: IVIG therapy in patients with COVID19-related moderate-severe ARDS was associated with higher ICU mortality. A randomized clinical trial is needed to further confirm this observation.
ABSTRACT
Background: Clinical trial registries ensure the transparency and accountability of clinical trials (CTs) internationally1-2. It is important to safeguard the public's safety through the delivery of quality clinical research. Since the start of the COVID-19 pandemic there has been a tremendous increase in the number of CTs globally. The MENA region has an opportunity to increase its overall contribution to CTs, which is less than 1%3, in particular, through Qatar given its substantial economical growth and healthcare advancements. This review aims to explore the characteristics of clinical trials performed in Qatar, registered on ClinicalTrials.gov. Methods: The ClinicalTrials.gov registry was searched for trials conducted in Qatar using the appropriate keywords and advanced search options. Data retrieved was downloaded and sorted within Microsoft Excel then reviewed by two independent co-investigators. Results: The preliminary search yielded 143 entries with 32.1% (46) registered as multisite trials. The first trial in Qatar was registered in 2005. There has been a noticeable increase in CTs with its peak in 2020 (Figure 1), with currently 39.1% (9) of registered CTs on COVID-19;83% of the completed studies were published, with the highest number of publications (8) in 2020 (Figure 1). Several specialties contributed to the CTs, with the highest participation and contribution rate of 31 CTs being in the field of pediatrics. Furthermore, some variations were found in recruitment status as reflected in Figure 2 with∼65% (93) of studies being interventional and∼35% being observational. Conclusion: The CTs conducted in Qatar are still relatively low despite the rapidly evolving healthcare system. Immediate updates and follow-ups could be considered by research investigators in Qatar with regards to CTs registration and updating. Further analysis is needed to elucidate the discrepancy of CTs reporting and to increase the contribution of CTs from Qatar to improve the health of its people.